Tuesday, 5 July 2011

Porphyrias , creatinine elevation


In the Phasted State

Phosphorylate Phosphorylation cascade active when blood glucose low.
DNA expression into mature mRNA
Exons expressed, Introns in the trash.
Pyrimidines are CUT from purines.
Pyrimidines are Cytosine, Uracil, Thiamine and are one ring structures.
Purines are double ring structures.

Porphyrias: acute intermittent porphyria symptoms 5 P's:
Pain in abdomen
Polyneuropathy
Psychologial abnormalities
Pink urine
Precipitated by drugs (eg barbiturates, oral contraceptives, sulpha drugs)

BUN:creatinine elevation: causes ABCD: 


Azotremia (pre-renal)
Bleeding (GI)
Catabolic status
Diet (high protein parenteral nutrition)


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